CD3 Antikörper

Produktnummer ABIN2567500

Dieser Anti-CD3 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD3 in FACS, IHC und Func. Geeignet für Human.

Kurzübersicht für CD3 Antikörper (ABIN2567500)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Klon: OKT3

Produktdetails anti-CD3 Antikörper

Spezifität: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C. Do not freeze.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

Gen-ID: 916

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway